6H05 (TFA)
6H05 TFA is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).IC50 value:Target: K-Ras G12C6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras . 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors .